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Use of DMBA in Animals - Environment, Health and …

Use of DMBA in Animals PURPOSE: ... • If DMBA solution is splashed on an individual or in eyes flush for 15 minutes with copious quantities of water and contact the University Employee Occupational Health ... Melting point 122 - 123 °C (252 - 253 °F) - lit. Boiling point no data available
ehs.unc.edu/files/2015/09/dmba.pdf

7,12-Dimethylbenz[a]anthracene ≥95% | Sigma-Aldrichhttps://www.sigmaaldrich.com/catalog/product/sigma/d3254The oxidation of DMBA by P450 enzymes produces metabolites that form covalent adducts with DNA and the formation within DNA of depurinated abasic sites. It is most commonly used to induce skin or mammary tumors in animals, though it also can induce leukemias and tumors at other sites.

The oxidation of DMBA by P450 enzymes produces metabolites that form covalent adducts with DNA and the formation within DNA of depurinated abasic sites. It is most commonly used to induce skin or mammary tumors in animals, though it also can induce leukemias and tumors at other sites.
www.sigmaaldrich.com/catalog/product/sigma/d3254

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DMBA | C20H16 | ChemSpiderwww.chemspider.com/Chemical-Structure.5779.htmlA tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke. ChEBI CHEBI:254496

A tetraphene having methyl substituents at the 7- and 12-positions. It is a potent carcinogen and is present in tobacco smoke. ChEBI CHEBI:254496
www.chemspider.com/Chemical-Structure.5779.html

7,12-Dimethylbenzanthracene | C20H16 - PubChempubchem.ncbi.nlm.nih.gov › compoundSix hours after DMBA administration, the blood levels of DMBA in mice fed the SBR diet were significantly lower than mice fed a control diet. DMBA reduced bone marrow cells in mice fed control diet to a significantly greater extent than mice fed the SBR diet.

Six hours after DMBA administration, the blood levels of DMBA in mice fed the SBR diet were significantly lower than mice fed a control diet. DMBA reduced bone marrow cells in mice fed control diet to a significantly greater extent than mice fed the SBR diet.
7,12-Dimethylbenzanthracene | C20H16 - PubChempubc...

Iron Deficiency Alters DMBA-Induced Tumor Burden and ...https://academic.oup.com/jn/article/122/1/46/4754759A pair-fed group was fed the 42 mg Fe/kg diet at the level consumed by the 8 mg Fe/kg group. Following 6 wk of dietary treatment, DMBA-treated rats received a single intragastric dose of DMBA. Dietary treatment was continued. Rats were killed at 1, 4, 8, 14 and 20 wk post-DMBA treatment.

A pair-fed group was fed the 42 mg Fe/kg diet at the level consumed by the 8 mg Fe/kg group. Following 6 wk of dietary treatment, DMBA-treated rats received a single intragastric dose of DMBA. Dietary treatment was continued. Rats were killed at 1, 4, 8, 14 and 20 wk post-DMBA treatment.
academic.oup.com/jn/article/122/1/46/4754759

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7,12-Dimethylbenz(a)anthracene - an overview ...https://www.sciencedirect.com/.../7-12-dimethylbenz-a-anthracene7,12-Dimethylbenz(a)anthracene (DMBA), ultraviolet B irradiation, ... AP-1 is a primary target for EGCG in preventing skin cancer at the tumor promotion stage. 122. Read full chapter. Bamboo Extract in the Prevention of Diabetes and Breast Cancer. Jun Panee, in Complementary and Alternative Therapies and the Aging Population, 2009.

7,12-Dimethylbenz(a)anthracene (DMBA), ultraviolet B irradiation, ... AP-1 is a primary target for EGCG in preventing skin cancer at the tumor promotion stage. 122. Read full chapter. Bamboo Extract in the Prevention of Diabetes and Breast Cancer. Jun Panee, in Complementary and Alternative Therapies and the Aging Population, 2009.
www.sciencedirect.com/.../7-12-dimethylbenz-a-anth...

7,12-Dimethylbenz(a)anthracene - Wikipediahttps://en.wikipedia.org/wiki/7,12-Dimethylbenz(a)anthracene7,12-Dimethylbenz[a]anthracene (DMBA) is an immunosuppressor and a powerful organ-specific laboratory carcinogen. DMBA is widely used in many research laboratories studying cancer. DMBA serves as a tumor initiator .CAS Number: 57-97-6

7,12-Dimethylbenz[a]anthracene (DMBA) is an immunosuppressor and a powerful organ-specific laboratory carcinogen. DMBA is widely used in many research laboratories studying cancer. DMBA serves as a tumor initiator .
en.wikipedia.org/wiki/7,12-Dimethylbenz(a)anthrace...

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